Topic outline

  • General

  • Welcome to Module A — Biotechnology

    Science

    “Nature” has had millions of years to solve problems. Using biotechnology, scientists and engineers take advantage of what nature has already done and expand on it. As a result, they have figured out how to use biotechnology to solve a variety of problems ranging from common every day problems such as

    • Cleaning clothes more effectively with detergents that contain enzymes
    • Fixing a gene that causes cystic fibrosis so a person can breathe better
    • Mass-producing genetically engineered insulin
    • Developing renewable fuels
    • Genetically altering corn so that herbicides or insecticides can be sprayed across the field and only kill the weeds or pests

    Of course, using these technologies involves weighing the trade-offs between the positive and negative effects. These technologies did not appear by accident. They are developed over long periods of time with an abundance of research, design practices and collaboration among people from  different fields.

    What will I learn in this course?

    In this course, you will be introduced to the fields of biotechnology and engineering. Lastly, you will use what you have learned to design, build, and test a fully functional bioreactor which can be used to mass produce medicines or generate alternative fuels. You will be the engineer.

    Over the next eight weeks you will:

    • Discover how science, technology and engineering come together to help solve problems
    • Explore different fields of biotechnology and its applications in your life
    • Review basic biology and engineering principles
    • Create an artificial source of insulin using biotechnology and engineering techniques
    • Work as a team to design, build, test and evaluate a bioreactor in your own classroom
    • Experience what its like work as a biotechnician
    • Use technology to solve problems
    Folder: 1
  • Section 1 Introduction

    To Complete Section 1:

    1. Obtain Section 1 Guided Reading Notes
    2. Complete Lesson 1 Guided Reading Notes as you review Lesson 1.1 and Lesson 1.2
    3. Submit Guided Reading Notes according to you teacher's instructions
    4. Complete Section 1 QUIZ. You have TWO attempts to take the quiz. Your highest score will be recorded.
    5. Complete Extension activities as assigned by your teacher

    Folders: 2Glossary: 1Lessons: 2Quiz: 1Forum: 1
  • Section 2 The Design Process

    Phase 1 Phase 2 Phase 3 Phase 4 Phase 5 Phase 6 Phase 7 Phase 8

    Informed Design Process=

    Let’s take a closer look at each step of the engineering design process and how it will help you once you enter start to solve your design challenge. Unlike solving a math problem or testing a scientific hypothesis, this process is non-linear, as is typical of any creative process. Notice the inner arrows in the figure below; these indicate that at any time in the process, it is fine to go back and add, change or take away information.

    To Complete Section 2:

    1. Obtain Section 2 Guided Reading Notes
    2. Complete Lesson 2 Guided Reading Notes as you review Lesson 2.0-Lesson 2.8 
    3. Submit Guided Reading Notes according to you teacher's instructions
    4. Complete Section 2 QUIZ. You have TWO attempts to take the quiz. Your highest score will be recorded.
    5. Complete Extension activities as assigned by your teacher
    Folders: 2Glossary: 1Lessons: 9Quiz: 1Forums: 2File: 1
  • Section 3 What is Biotechnology?

    To Complete Section 3:

    1. Obtain Section 3 Guided Reading Notes
    2. Complete Lesson 3 Guided Reading Notes as you review Lesson 3.1-Lesson 3.3 
    3. Submit Guided Reading Notes according to you teacher's instructions
    4. Complete Section 3 QUIZ. You have TWO attempts to take the quiz. Your highest score will be recorded.
    5. Complete Extension activities as assigned by your teacher
    Folders: 2Glossary: 1Lessons: 3Quiz: 1Forums: 3URL: 1
  • Section 4 Biology Review

     To Complete Section 4:

    1. Complete Pre-Test Biology
    2. If you score an 80% or higher move onto Section 5.
    3. If you score below 80%, continue instructions below.
    4. Obtain Section 4 Guided Reading Notes
    5. Complete Lesson 4 Guided Reading Notes as you review Lesson 4.1-Lesson  4.9
    6. Submit Guided Reading Notes according to you teacher's instructions
    7. Complete Section 4 QUIZ. You have TWO attempts to take the quiz. Your highest score will be recorded.
    8. Complete Extension activities as assigned by your teacher
    Quizzes: 2Folders: 2Glossary: 1Lessons: 9URLs: 2Forum: 1
  • Section 5 Biomanufacturing: The Story of Insulin

     

    To Complete Section 5:

    1. Obtain Section 5 Activity Handout titled "The Story of Insulin."
    2. Complete Lesson 5 Activity by Viewing Lesson 5.1.
    3. Submit Lesson 5 Activity as specified by your teacher.
    4. Complete Section 5 QUIZ. You have TWO attempts to take the quiz. Your highest score will be recorded.
    5. Complete Extension activities as assigned by your teacher.
    File: 1Lesson: 1URL: 1Forum: 1Assignment: 1Folder: 1
  • Section 6 The Effects of Insulin

    Everyone's knowledge base on how the endocrine system works may be different. To make sure everyone has a foundation in this topic, this section has been developed. What does the graph below represent?

    To Complete Section 6:

    1. Complete Section 6 pre-quiz. This quiz will not count against your grade. It is simply a self-assessment so you can see where you need to focus in your studies.
    2. If you score less than a 90%, visit the Learning Resources below to master the content.
    3. Once you feel like you have mastered the materials in the pre-test, complete Section 5 post-test. This one WILL be graded. 

    Quizzes: 2URL: 1File: 1Folder: 1
  • Section 7 Biomanufacturing

    To Complete Section 7:

    1. Obtain Section 7 Guided Reading Notes
    2. Complete Section 7 Guided Reading Notes by viewing Lessons 7.1 to 7.4
    3. Submit Lesson 7 Notes according to you teacher's instructions
    4. Complete Section 7 QUIZ. You have TWO attempts to take the quiz. Your highest score will be recorded.
    5. Complete Extension activities as assigned by your teacher
    File: 1Glossary: 1Lessons: 4Quiz: 1Forum: 1URL: 1Folder: 1
  • Section 8 Protein Purification

    Below are the basic steps that could be taken to isolate and purify a protein from an organ sample. These steps are simple and flexible. They will vary depending on the chemical and physical components of your protein and the protein source. The strategies in this lesson focus on target proteins, such as insulin, for purification

    Just like any lab performed whether in a classroom or industry, training of the process and equipment is vital for lab safety, efficiency and product quality assurance. This is what you will do in this lesson. 

    To Complete Section 8:

    1. Collect the Section 8 Insulin Flow Chart Pieces and Section 8 Guided Reading Notes notes from your instructor. Copies are also below.
    2. Cut out all flow chart pieces
    3. Complete Section 8 Guided Reading Notes while building a purification flow chart as you work through Lesson 8.1 Protein Purification
    4. Organize the flow chart pieces into a sample purification scheme
    5. Capture and submit flow chart to assignment folder titled "Protein Purification Chart"
    6. Complete Section 8 quiz. You have TWO attempts. The highest attempt will be saved.

    Files: 2Glossary: 1Lesson: 1Assignment: 1Quiz: 1URL: 1Folder: 1
  • Section 9 Designer DNA: Solving the Insulin Problem

    To Complete Section 9:

    1. Obtain Section 9 Guided Reading Notes
    2. Complete Lesson 9 Guided Reading Notes as you review Lesson 10.1
    3. Submit Guided Reading Notes according to you teacher's instructions
    4. Complete The Story Insulin Webquest document
    5. Complete Section 9 QUIZ. You have TWO attempts to take the quiz. Your highest score will be recorded.
    6. Complete Extension activities as assigned by your teacher
    Folder: 1Glossary: 1Lessons: 3Quizzes: 2Files: 2URL: 1
  • Section 11 Product Redesign and Maximizing Product Production

    6.0.1.1

    The products of biotechnology are typically designed for some type of agricultural, commercial, or medical use. Success of a biotechnology product is based on its improvement over similar traditionally made products. For example, the Flavr Savr tomatoes ripened much more slowly than traditional tomatoes. This increased their storage life and caused them to bruise less when shipped from the farm to the market. However, marketing biotechnology products is more challenging than marketing traditional products because of negative public sentiment promoted by various public interest groups.

    A large part of marketing a biotechnology product is ensuring that the product does what it claims without causing unnecessary harm to humans and the environment. For example, genetically modified insulin must be shown by experimentation to be effective at reducing blood sugar in a similar manner to a person’s natural insulin produced by the pancreas. In addition, the insulin should not knowingly cause any harm that exceeds the benefits of its use. Biotechnology products also need a certain degree of purity so that they do not contain any contaminants that can harm people or the environment. Like traditionally produced foods, ingredient lists are important for biotechnology food products. In some areas, these labels may have to include a statement that the food was produced through genetic modification.

    File: 1Glossary: 1Lessons: 6Assignments: 3Quiz: 1Folder: 1